A Low Power Architectural Framework for Automated Surveillance System with Low Bit Rate Transmission

Abstract The changed security scenario of the modern time has necessitated increased and sophisticated vigilance of the countries' borders. The technological challenges involved in accomplishing such feat of automated security system are many and require research at the components-and-algorithms as well as the architectural levels.  This paper proposes an architectural framework for automated video surveillance comprising a network of sensors and closed circuit television cameras as well as proposing algorithmic/component research of software and hardware for the core functioning of the framework, such as: communication protocols, object detection, data-integration, object identification, object tracking, video compression, threat identification, and alarm generation. In this paper, we are addressing some general topological and routing features that would be adopted in our system. There are two types of data with regard to data communication – video stream and object detection. The network is broken down into several disjoint, almost equal zones. A zone have one or more one cluster. A zone manager is chosen among the cluster heads depending on their relative residual energies. There are several levels of control that could be implemented with this arrangement with localized decision made, to get distributed effect at all levels. A cell tracks each target in its zone. If the target moves out of the range of a cell, the cell manager will send the target description to estimated next cell. The next cell starts tracking the target. If the estimated cell is wrongly chosen, corrections will be made by the cluster heads to get the new target-tracking. We also propose bitrate reduction algorithms to accommodate the limited bandwidth. One of the main feature of this paper is introducing a Low-Power Low-Bit rate video compression algorithm to accommodate the low power requirements at sensor nodes, and the low bit rate requirement for the communication protocol. We proposed two algorithms the ALBR and LPHSME. ALBR is addressing low bit rate required for sensors network with limited bandwidth which achieves a reduction in Average number of bits per Iframe by approximately 60% in case of low motion video sequences and 53% in case of fast motion video sequences . LPHSME addresses low power requirements of multi sensor network that has limited power batteries. The performance of the proposed LPHSME algorithm versus full search and three step search indicates  a reduction in motion estimation time by approximately 89% in case of low motion video sequences (e.g., Claire ) and 84% in case of fast motion video sequences. The reduced complexity of  LPHSME results in low power requirements

Signaling mechanisms of a water soluble curcumin derivative in experimental type 1 diabetes with cardiomyopathy

BACKGROUND: Curcumin exhibits anti-diabetic activities, induces heme-oxygenase-1 (HO-1) and is an inhibitor of transcriptional co-activator p300. A novel water soluble curcumin derivative (NCD) has been developed to overcome low invivo bioavailability of curcumin. We evaluated the effect of the NCD on signaling mechanisms involved in cardiomyocyte hypertrophy and studied whether its action is mediated via inducible HO-1. MATERIALS AND METHODS: Rats were divided into controls, controls receiving NCD, diabetic, diabetic receiving NCD, diabetic receiving pure curcumin, diabetic receiving HO inhibitor, zinc protoporphyrin IX (ZnPP IX) and diabetic receiving NCD and ZnPP IX. NCD and curcumin were given orally. After 45 days, cardiac physiologic parameters, plasma glucose, insulin, glycated hemoglobin (GHb), HO-1 gene expression and HO activity in pancreas and cardiac tissues were assessed. Gene expression of p300, atrial natriuretic peptide (ANP) and myocyte enhancer factor 2 (MEF2A and MEF2C) were studied. RESULTS: NCD and curcumin decreased plasma glucose, GHb and increased insulin levels significantly in diabetic rats. This action may be partially mediated by induction of HO-1 gene. HO-1 gene expression and HO activity were significantly increased in diabetic heart and pancreas. Diabetes upregulated the expression of ANP, MEF2A, MEF2C and p300. NCD and curcumin prevented diabetes-induced upregulation of these parameters and improved left ventricular function. The effect of the NCD was better than the same dose of curcumin

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Computerized Prediction of Perovskite Performance Using Deep Learning

Perovskites have exceptional physical and chemical features in different fields. Perovskites have an ABO3 formula with similar sizes of A-site and B-site cations. This research explores the challenges of developing new perovskite solar cells with high performance. Therefore, this article proposes a deep learning model for the prediction of perovskites performance measures. The measures are: energy conversion performance, ABO3 stability, ion volume, and induced oxygen vacancy dimension. These performance measures are very crucial electrochemical reactions in energy conversion in fuel crystals. The challenges in any deep learning model are the lack of the presence of sufficient data and training time. Consequently, in this research, we propose a transfer learning perovskites model. Perovskite performance detection is critical to offer operative energy resources. In the proposed model, the constructed detection model uses a perovskites feature set. The transfer learning model utilizes other materials with large-sized datasets to predict the four performance measures with high accuracy. The output of the transfer learning is then utilized for the proposed deep learning model to predict perovskites performance measures with a small-sized dataset. A dataset of 8500 perovskite samples is utilized in the research. The results prove that a deep learning F2-Score with transfer learning attains high accuracy of 98.95%, recall of 96.91% and F2-score of 97.05%

Methodology for Exploring Patterns of Epigenetic Information in Cancer Cells Using Data Mining Technique

Epigenetic changes are a necessary characteristic of all cancer types. Tumor cells usually target genetic changes and epigenetic alterations as well. It is most beneficial to identify epigenetic similar features among cancer various types to be able to discover the appropriate treatments. The existence of epigenetic alteration profiles can aid in targeting this goal. In this paper, we propose a new technique applying data mining and clustering methodologies for cancer epigenetic changes analysis. The proposed technique aims to detect common patterns of epigenetic changes in various cancer types. We demonstrated the validation of the new technique by detecting epigenetic patterns across seven cancer types and by determining epigenetic similarities among various cancer types. The experimental results demonstrate that common epigenetic patterns do exist across these cancer types. Additionally, epigenetic gene analysis performed on the associated genes found a strong relationship with the development of various types of cancer and proved high risk across the studied cancer types. We utilized the frequent pattern data mining approach to represent cancer types compactly in the promoters for some epigenetic marks. Utilizing the built frequent pattern item set, the most frequent items are identified and yield the group of the bi-clusters of these patterns. Experimental results of the proposed method are shown to have a success rate of 88% in detecting cancer types according to specific epigenetic pattern

Computerized Detection of Calcium Oxalate Crystal Progression

Calcium oxalate crystals in plants can cause health issues such as kidney stones if ingested in large amounts. Calcium oxalate crystallizations affect approximately 4% of plants. Some of these crystallizations are more common, and human and animal ingestion can be avoided if the degree of severity is detected at an early stage. Therefore, in this paper, we present a computerized method for detecting calcium oxalate crystallizations at an early stage, when chances for avoiding it are higher. In our research, electron micrograph processing techniques are used to extract features and measure the degree of crystallization progression in cases of crystalized plants and normal plants. A new fast search algorithm&mdash;ODS: One Direction Search&mdash;is proposed to detect calcium oxalate crystal progression. The calcium oxalate crystal progression is detected on the basis of electron micrographs of calcium oxalate crystals by means of a temporal test. We employed deep learning for feature extraction. The deep learning technique uses transfer learning, which allows the proposed detection model to be trained on only a small amount of data regarding calcium oxalate crystals for the determination of the presence of calcium oxalate crystals and the severity of the cases. The experimental results, using electron micrographs of 6900 clusters, demonstrated a success rate of 97.5% when detecting cases of calcium oxalate crystals. The simulation results of the new temporal algorithm show an enhancement of the speed by 70% compared to well-known temporal algorithms, and increased accuracy when computing PRSN against other algorithms

Diabetic Retinopathy Progression Prediction Using a Deep Learning Model

Diabetes is an illness that happens with a high level of glucose in the body, and can harm the retina, causing permanent loss vision or diabetic retinopathy. The fundus oculi method comprises detecting the eyes to perform a pathology test. In this research, we implement a method to predict the progress of diabetic retinopathy. There is a research gap that exists for the detection of diabetic retinopathy progression employing deep learning models. Therefore, in this research, we introduce a recurrent CNN (R-CNN) model to detect upcoming visual field inspections to predict diabetic retinopathy progression. A benchmark dataset of 7000 eyes from healthy and diabetic retinopathy progress cases over the years are utilized in this research. Approximately 80% of ocular cases from the dataset is utilized for the training stage, 10% of cases are used for validation, and 10% are used for testing. Six successive visual field tests are used as input and the seventh test is compared with the output of the R-CNN. The precision of the R-CNN is compared with the regression model and the Hidden Markov (HMM) method. The average prediction precision of the R-CNN is considerably greater than both regression and HMM. In the pointwise classification, R-CNN depicts the least classification mean square error among the compared models in most of the tests. Also, R-CNN is found to be the minimum model affected by the deterioration of reliability and diabetic retinopathy severity. Correctly predicting a progressive visual field test with the R-CNN model can aid physicians in making decisions concerning diabetic retinopathy

Machine Translation Utilizing the Frequent-Item Set Concept

In this paper, we introduce new concepts in the machine translation paradigm. We treat the corpus as a database of frequent word sets. A translation request triggers association rules joining phrases present in the source language, and phrases present in the target language. It has to be noted that a sequential scan of the corpus for such phrases will increase the response time in an unexpected manner. We introduce the pre-processing of the bilingual corpus through proposing a data structure called Corpus-Trie (CT) that renders a bilingual parallel corpus in a compact data structure representing frequent data items sets. We also present algorithms which utilize the CT to respond to translation requests and explore novel techniques in exhaustive experiments. Experiments were performed on specific language pairs, although the proposed method is not restricted to any specific language. Moreover, the proposed Corpus-Trie can be extended from bilingual corpora to accommodate multi-language corpora. Experiments indicated that the response time of a translation request is logarithmic to the count of unrepeated phrases in the original bilingual corpus (and thus, the Corpus-Trie size). In practical situations, 5–20% of the log of the number of the nodes have to be visited. The experimental results indicate that the BLEU score for the proposed CT system increases with the size of the number of phrases in the CT, for both English-Arabic and English-French translations. The proposed CT system was demonstrated to be better than both Omega-T and Apertium in quality of translation from a corpus size exceeding 1,600,000 phrases for English-Arabic translation, and 300,000 phrases for English-French translation